This research paper discusses the origin of nursing the developments of nursing through different generations with a specific comparison between 20th and the 21st century. Nursing has gone substantial developments which have been propelled by economic and technological growth. The research was qualitative hence secondary data was used to reach the conclusions. The research has reviewed literature which clearly indicates that nursing has tremendously changed. The profession is now taught and the roles have changed to fit the circumstances of the time. At a time when nursing is changing new challenges of eroding the ethics are witnessed. The change in nursing has its associated challenges which have been assessed and various conclusions reached. There are specific recommendations which if considered the challenges will be addressed ably.IntroductionThere is an agreeable position to the effect that nursing has shown its usefulness through preservation of health. In addition restoration of health has been achieved through different phases in time. With the drastic changes in the nursing profession today it is worth examining the historical origin of nursing. Arguably the nursing profession is said to have its history pegged on the history of Christianity and specifically the history of Christian church. This notion is grounded in the understanding that Christian values taught taking care of the sick as a virtue. This research mainly seeks to explore the comparison of the nursing during the twentieth century and the twenty first century (Lori para 4).It is asserted that the end of 19th century marked a fundamental shift on the perception of health whereby healthcare providers made efforts to improve sanitation. In addition the health of communities was given a leading role. The 20th Century was a period whereby break through in the discovery of antibiotics shaped the health care since different ways of countering infections were established. The main priority of health care changed from the concern being the wellbeing of the community to an individual consideration. The caring of the patient in the community was extensively increased. (Lundy Karen and Sharyn 532-535).It is still in the 20th Century whereby technological advancement defined the mode of approaching diseases by health care providers. The insurance part of it made individual concerns well catered for through an insurance cover. On the other hand the increase in health care cost marked a period of ethical issues whereby it had to be determined who to receive health care basing on the individuals social economic status and age. The said consideration has found its way to the 21st century health care sector. (Fags.org Para. 3).The formation of the International Red Cross In 1864 was a major eye opener the entire world and that instigated massive training of nurses all over the world. At its origin nursing had been dominated by religious groups in the early 20th Century United States placed proper training on nurses hence changing the trend. Classes of nursing increased through out Canada and United States and nursing instructions were given in classrooms. Hospitals became the source of employment to nurses who graduated from the said colleges. Unlike there before a nurse became a person well versed with the essentials of treating and taking care of a patient (Lori para 7).